One pattern that emerges over and over in our interviews with scientists involved in biotech is that ideas for companies often involve scientists creating something — a method, a reagent, a type of molecule, etc. — for use in basic research, finding that they are using it more often than they thought, that other people are asking them for it, and in the end the requests become frequent enough and the volume large enough that someone within the lab suggests founding a company to produce them and sell them to other scientists. This was the case for Stony Brook chemistry professor Glenn Prestwich, who in the course of a collaboration with a neuroscientist colleague worked out a way to produce a specific kind of molecule labeled in a specific way that was useful to huge numbers of researchers. In the late 1990s, he and a colleague at the University of Utah ended up founding a company, Echelon Biosciences, “to make these molecules that biologists needed. Our postdocs were getting tired of making them over and over again.”

Prestwich / Stony Brook Center for Biotechnology

Plants need nitrogen to grow, but a significant portion of the nitrogen in fertilizers is not absorbed by the soil or used by the growing plants. Rather, it washes away into waterways, rivers, and the ocean. This in turn has had devastating effects on marine life. In some areas, excessive nitrogen in the oceans has caused algae blooms that kill wildlife, make it dangerous for people to consume fish or shellfish or in some cases even swim in affected waters. This problem isn’t limited to poorer countries. Nitrogen pollution is a serious problem here on Long Island. In our case, the nitrogen comes primarily from septic tanks and cesspools, although nitrogen from agricultural fertilizers also plays a role. Nitrogen pollution in the waters around Long Island has hampered fishing, made it dangerous to eat seafood from some areas, and caused environmental changes that make coastal areas more prone to flooding.